Fiat lux

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چکیده

Just as engineers learnt to harness the power of electrons in transistors and microchips—which revolutionized modern society—physicists and biologists are now learning how to tame photons. Their work is generating exciting new possibilities for optical microscopy, with a resolution and level of detail hitherto undreamt of. Biophotonics is a new and exciting research field that is already delivering substantial dividends in a wide range of applications from fundamental medical research to diagnosis, therapy and surgery. For a long time the resolution of optical microscopes had been considered to be insufficient for most biological research applications. Consequently, optical microscopes were largely confined to classrooms and pathology laboratories until innovations, such as fluorescence microscopy and laser confocal microscopy, began to bring biophotonics back into the light. In combination with computerassisted image analysis and improved sample preparation methods (Hunter, 2005), various other technological advances have provided even higher levels of resolution and accuracy. These have allowed optical techniques to capitalize on the advantage that they always had over X-ray crystallography or electron microscopy—the ability to observe biochemical processes in real time.

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تاریخ انتشار 2013